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Differential antigenic requirements by diverse MR1‐restricted T cells

MHC‐related protein 1 (MR1) presents microbial riboflavin metabolites to mucosal‐associated invariant T (MAIT) cells for surveillance of microbial presence. MAIT cells express a semi‐invariant T‐cell receptor (TCR), which recognizes MR1–antigen complexes in a pattern‐recognition‐like manner. Recentl...

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Detalles Bibliográficos
Autores principales: Seneviratna, Rebecca, Redmond, Samuel J, McWilliam, Hamish EG, Reantragoon, Rangsima, Villadangos, Jose A, McCluskey, James, Godfrey, Dale I, Gherardin, Nicholas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033883/
https://www.ncbi.nlm.nih.gov/pubmed/34940995
http://dx.doi.org/10.1111/imcb.12519