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Rigid 3D-spiro chromanone as a crux for efficient antimicrobial agents: synthesis, biological and computational evaluation

The development of new and effective antimicrobial agents with novel chemical skeletons and working mechanisms is highly desirable due to the increased number of resistant microbes. Different new compounds based upon a 3D-spiro chromanone scaffold such as Mannich bases 2 and 3 in addition to azo dye...

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Detalles Bibliográficos
Autores principales: Elghareeb, F. H., Kandil, E. M., Abou-Elzahab, M., Abdelmoteleb, M., Abozeid, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034028/
https://www.ncbi.nlm.nih.gov/pubmed/35478839
http://dx.doi.org/10.1039/d1ra03497a