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Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90
Enzymes within the de novo purine biosynthetic pathway spatially organize into dynamic intracellular assemblies called purinosomes. The formation of purinosomes has been correlated with growth conditions resulting in high purine demand, and therefore, the cellular advantage of complexation has been...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034097/ https://www.ncbi.nlm.nih.gov/pubmed/35307352 http://dx.doi.org/10.1016/j.jbc.2022.101845 |