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Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion
Abnormal cellular copper levels have been clearly implicated in genetic diseases, cancer, and neurodegeneration. Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with a sophisticated copper transpo...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034245/ https://www.ncbi.nlm.nih.gov/pubmed/35202609 http://dx.doi.org/10.1016/j.bpj.2022.02.033 |