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Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion

Abnormal cellular copper levels have been clearly implicated in genetic diseases, cancer, and neurodegeneration. Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with a sophisticated copper transpo...

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Detalles Bibliográficos
Autores principales:	Walke, Gulshan, Aupič, Jana, Kashoua, Hadeel, Janoš, Pavel, Meron, Shelly, Shenberger, Yulia, Qasem, Zena, Gevorkyan-Airapetov, Lada, Magistrato, Alessandra, Ruthstein, Sharon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034245/ https://www.ncbi.nlm.nih.gov/pubmed/35202609 http://dx.doi.org/10.1016/j.bpj.2022.02.033

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