Aberrant overexpression of HOTAIR inhibits abdominal adipogenesis through remodelling of genome-wide DNA methylation and transcription

OBJECTIVE: Abdominal adiposity is strongly associated with diabetic and cardiovascular comorbidities. The long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is an important epigenetic regulator with fat depot-specific expression. Its functional roles and epigenetic regulation in abd...

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Detalles Bibliográficos
Autores principales: Kuo, Feng-Chih, Huang, Yu-Chun, Yen, Ming-Ren, Lee, Chien-Hsing, Hsu, Kuo-Feng, Yang, Hsiang-Yu, Wu, Li-Wei, Lu, Chieh-Hua, Hsu, Yu-Juei, Chen, Pao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034304/
https://www.ncbi.nlm.nih.gov/pubmed/35292404
http://dx.doi.org/10.1016/j.molmet.2022.101473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034304/
https://www.ncbi.nlm.nih.gov/pubmed/35292404
http://dx.doi.org/10.1016/j.molmet.2022.101473

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