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Water-promoted dehydrative coupling of 2-aminopyridines in heptane via a borrowing hydrogen strategy
A synthetic method for dehydrative N-benzylation promoted by water molecules in heptane using a π-benzylpalladium system has been developed. The presence of water significantly accelerates carbon–nitrogen bond formation, which is accomplished in an atom-economical process to afford the corresponding...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034306/ https://www.ncbi.nlm.nih.gov/pubmed/35480450 http://dx.doi.org/10.1039/d1ra04118e |