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Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is linked to impaired lipid metabolism and systemic insulin resistance, which is partly mediated by altered secretion of liver proteins known as hepatokines. Regular physical activity can resolve NAFLD and improve its metabolic comorbidities, howe...

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Detalles Bibliográficos
Autores principales: De Nardo, William, Miotto, Paula M., Bayliss, Jacqueline, Nie, Shuai, Keenan, Stacey N., Montgomery, Magdalene K., Watt, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034320/
https://www.ncbi.nlm.nih.gov/pubmed/35381388
http://dx.doi.org/10.1016/j.molmet.2022.101491