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Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism
OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is linked to impaired lipid metabolism and systemic insulin resistance, which is partly mediated by altered secretion of liver proteins known as hepatokines. Regular physical activity can resolve NAFLD and improve its metabolic comorbidities, howe...
Autores principales: | De Nardo, William, Miotto, Paula M., Bayliss, Jacqueline, Nie, Shuai, Keenan, Stacey N., Montgomery, Magdalene K., Watt, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034320/ https://www.ncbi.nlm.nih.gov/pubmed/35381388 http://dx.doi.org/10.1016/j.molmet.2022.101491 |
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