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Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disease that impacts nearly 400 million people worldwide. The accumulation of amyloid beta (Aβ) in the brain has historically been associated with AD, and recent evidence suggests that neuroinflammation plays a central role in i...

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Detalles Bibliográficos
Autores principales: Quiroga, I. Y., Cruikshank, A. E., Bond, M. L., Reed, K. S. M., Evangelista, B. A., Tseng, J. H., Ragusa, J. V., Meeker, R. B., Won, H., Cohen, S., Cohen, T. J., Phanstiel, D. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034485/
https://www.ncbi.nlm.nih.gov/pubmed/35459147
http://dx.doi.org/10.1186/s12974-022-02459-1