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Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems
BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disease that impacts nearly 400 million people worldwide. The accumulation of amyloid beta (Aβ) in the brain has historically been associated with AD, and recent evidence suggests that neuroinflammation plays a central role in i...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034485/ https://www.ncbi.nlm.nih.gov/pubmed/35459147 http://dx.doi.org/10.1186/s12974-022-02459-1 |