Increased testicular insulin-like growth factor 1 is associated with gonadal activation by recombinant growth hormone in immature rats

BACKGROUND: In children, recombinant human growth hormone (rhGH) therapy for treatment of short stature has raised concerns of the early onset of puberty. Puberty is initiated by the activation of the hypothalamus-pituitary-gonad axis. Insulin-like growth factor-1 (IGF1) has been known to mediate ph...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Han, Chang Yong, Park, Mi Jung, Gye, Myung Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034493/
https://www.ncbi.nlm.nih.gov/pubmed/35459135
http://dx.doi.org/10.1186/s12958-022-00944-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034493/
https://www.ncbi.nlm.nih.gov/pubmed/35459135
http://dx.doi.org/10.1186/s12958-022-00944-z

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