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Increased testicular insulin-like growth factor 1 is associated with gonadal activation by recombinant growth hormone in immature rats

BACKGROUND: In children, recombinant human growth hormone (rhGH) therapy for treatment of short stature has raised concerns of the early onset of puberty. Puberty is initiated by the activation of the hypothalamus-pituitary-gonad axis. Insulin-like growth factor-1 (IGF1) has been known to mediate ph...

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Detalles Bibliográficos
Autores principales:	Xu, Yang, Han, Chang Yong, Park, Mi Jung, Gye, Myung Chan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034493/ https://www.ncbi.nlm.nih.gov/pubmed/35459135 http://dx.doi.org/10.1186/s12958-022-00944-z

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