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Aryl hydrocarbon receptor activation ameliorates experimental colitis by modulating the tolerogenic dendritic and regulatory T cell formation

BACKGROUND: Intestinal immune dysfunction is involved in the onset of Crohn’s disease (CD). Dendritic cells (DCs), antigen-presenting cells, play a key role in the maintenance of intestinal immune homeostasis. The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor widely expr...

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Detalles Bibliográficos
Autores principales: Cui, Xiufang, Ye, Ziping, Wang, Di, Yang, Yan, Jiao, ChunHua, Ma, Jingjing, Tang, Nana, Zhang, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034494/
https://www.ncbi.nlm.nih.gov/pubmed/35461286
http://dx.doi.org/10.1186/s13578-022-00780-z