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PPARβ/δ priming enhances the anti-apoptotic and therapeutic properties of mesenchymal stromal cells in myocardial ischemia–reperfusion injury

BACKGROUND: Mesenchymal Stromal Cells (MSC) have been widely used for their therapeutic properties in many clinical applications including myocardial infarction. Despite promising preclinical results and evidences of safety and efficacy in phases I/ II, inconsistencies in phase III trials have been...

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Detalles Bibliográficos
Autores principales: Sarre, Charlotte, Contreras-Lopez, Rafael, Nernpermpisooth, Nitirut, Barrere, Christian, Bahraoui, Sarah, Terraza, Claudia, Tejedor, Gautier, Vincent, Anne, Luz-Crawford, Patricia, Kongpol, Kantapich, Kumphune, Sarawut, Piot, Christophe, Nargeot, Joel, Jorgensen, Christian, Djouad, Farida, Barrere-Lemaire, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034535/
https://www.ncbi.nlm.nih.gov/pubmed/35461240
http://dx.doi.org/10.1186/s13287-022-02840-0