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Estimating RNA dynamics using one time point for one sample in a single-pulse metabolic labeling experiment

BACKGROUND: Over the past decade, experimental procedures such as metabolic labeling for determining RNA turnover rates at the transcriptome-wide scale have been widely adopted and are now turning to single cell measurements. Several computational methods to estimate RNA synthesis, processing and de...

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Detalles Bibliográficos
Autores principales: Hersch, Micha, Biasini, Adriano, Marques, Ana C., Bergmann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034570/
https://www.ncbi.nlm.nih.gov/pubmed/35459101
http://dx.doi.org/10.1186/s12859-022-04672-4