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Circular RNA circ-MTHFD1L induces HR repair to promote gemcitabine resistance via the miR-615-3p/RPN6 axis in pancreatic ductal adenocarcinoma

BACKGROUND: Chemoresistance of pancreatic cancer is the main reason for the poor treatment effect of pancreatic cancer patients. Exploring chemotherapy resistance-related genes has been a difficult and hot topic of oncology. Numerous studies implicate the key roles of circular RNAs (circRNAs) in the...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-Wen, Hu, Jian-Fei, Wang, Zu-Wei, Liao, Cheng-Yu, Kang, Feng-Ping, Lin, Cai-Feng, Huang, Yi, Huang, Long, Tian, Yi-Feng, Chen, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034615/
https://www.ncbi.nlm.nih.gov/pubmed/35459186
http://dx.doi.org/10.1186/s13046-022-02343-z