Cargando…

Inhibition of COX-2 ameliorates murine liver schistosomiasis japonica through splenic cellular immunoregulation

BACKGROUND: We have reported the positive association of the cyclooxygenase 2 (COX-2)/prostaglandin E2 (PGE2) axis with liver fibrosis induced by Schistosoma japonicum (Sj) infection, and TLR4 signaling controlled this axis. However, how COX-2 regulates immune response during Sj infection is still u...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Zhang, Lan, Chen, Xiaofang, Ji, Juanjuan, Tang, Cheng, Fu, Ting, Huang, Erxia, Shen, Zi, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034617/
https://www.ncbi.nlm.nih.gov/pubmed/35461268
http://dx.doi.org/10.1186/s13071-022-05201-1