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Inhibition of COX-2 ameliorates murine liver schistosomiasis japonica through splenic cellular immunoregulation
BACKGROUND: We have reported the positive association of the cyclooxygenase 2 (COX-2)/prostaglandin E2 (PGE2) axis with liver fibrosis induced by Schistosoma japonicum (Sj) infection, and TLR4 signaling controlled this axis. However, how COX-2 regulates immune response during Sj infection is still u...
Autores principales: | Qi, Zhang, Lan, Chen, Xiaofang, Ji, Juanjuan, Tang, Cheng, Fu, Ting, Huang, Erxia, Shen, Zi, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034617/ https://www.ncbi.nlm.nih.gov/pubmed/35461268 http://dx.doi.org/10.1186/s13071-022-05201-1 |
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