Cargando…

DNA Supercoiling Drives a Transition between Collective Modes of Gene Synthesis

Transcription of genes can be affected by both biochemical and mechanical factors. Recent experiments suggested that the mechanical stress associated with transcription-induced DNA supercoiling is responsible for the transition from cooperative to antagonistic group dynamics of RNA polymerases (RNAP...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Purba, Goldenfeld, Nigel, Kim, Sangjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034659/
https://www.ncbi.nlm.nih.gov/pubmed/34860091
http://dx.doi.org/10.1103/PhysRevLett.127.218101