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DNA Supercoiling Drives a Transition between Collective Modes of Gene Synthesis
Transcription of genes can be affected by both biochemical and mechanical factors. Recent experiments suggested that the mechanical stress associated with transcription-induced DNA supercoiling is responsible for the transition from cooperative to antagonistic group dynamics of RNA polymerases (RNAP...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034659/ https://www.ncbi.nlm.nih.gov/pubmed/34860091 http://dx.doi.org/10.1103/PhysRevLett.127.218101 |