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Microencapsulated Multifunctionalized Graphene Oxide Equipped with Chloroquine for Efficient and Sustained siRNA Delivery

A multifunctionalized graphene oxide (GO)-based carrier with conjugation of aminated-polyethylene glycol (PEG-diamine), octaarginine (R8), and folic acid (FA), which also contains chloroquine (CQ), a lysosomotropic agent, is introduced. The cellular uptake mechanisms and intracellular targeting of F...

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Detalles Bibliográficos
Autores principales: Imani, Rana, Prakash, Satya, Vali, Hojatollah, Presley, John F., Faghihi, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034959/
https://www.ncbi.nlm.nih.gov/pubmed/35469347
http://dx.doi.org/10.1155/2022/5866361