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eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damage

eIF3a (eukaryotic translation initiation factor 3a), a subunit of the eIF3 complex, has been suggested to play a regulatory role in protein synthesis and in cellular response to DNA-damaging treatments. S6K1 is an effector and a mediator of mTOR complex1 (mTORC1) in regulating protein synthesis and...

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Detalles Bibliográficos
Autores principales: Ma, Shijie, Dong, Zizheng, Huang, Yanfei, Liu, Jing-Yuan, Zhang, Jian-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035104/
https://www.ncbi.nlm.nih.gov/pubmed/35279705
http://dx.doi.org/10.1038/s41388-022-02262-5