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eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damage
eIF3a (eukaryotic translation initiation factor 3a), a subunit of the eIF3 complex, has been suggested to play a regulatory role in protein synthesis and in cellular response to DNA-damaging treatments. S6K1 is an effector and a mediator of mTOR complex1 (mTORC1) in regulating protein synthesis and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035104/ https://www.ncbi.nlm.nih.gov/pubmed/35279705 http://dx.doi.org/10.1038/s41388-022-02262-5 |