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Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy

Previous studies reported that RAGE participated in the process of kidney fibrosis, but the function and regulation pathway of RAGE in proximal tubular cells in this process remains unclear. Here, we found that expression of RAGE was increased by TGF-β1 treatment and unilateral ureteral obstruction...

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Detalles Bibliográficos
Autores principales: Liu, Bohao, Sun, Tianshi, Li, Huiling, Qiu, Shuangfa, Li, Yijian, Zhang, Dongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035155/
https://www.ncbi.nlm.nih.gov/pubmed/35461309
http://dx.doi.org/10.1038/s41419-022-04856-z