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Hyperglycemia induces gastric carcinoma proliferation and migration via the Pin1/BRD4 pathway

Diabetes is a potential risk factor for gastric cancer (GC). Pin1, a peptidyl–prolyl cis/trans isomerase, promotes GC cell proliferation and migration. The role and underlying mechanism of the Pin1/BRD4 axis in hyperglycemia-induced proliferation and migration of GC cells were analyzed in vivo and i...

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Detalles Bibliográficos
Autores principales: Yu, Jianjian, Hu, Dan, Wang, Laicheng, Fan, Zongcheng, Xu, Changsheng, Lin, Yunchai, Chen, Xin, Lin, Jinxiu, Peng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035156/
https://www.ncbi.nlm.nih.gov/pubmed/35461311
http://dx.doi.org/10.1038/s41420-022-01030-4