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Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy

BACKGROUND: Immunotherapy in colorectal cancer (CRC) regulates specific immune checkpoints and, when used in combination with chemotherapy, can improve patient prognosis. One specific immune checkpoint is the recruitment of circulating monocytes that differentiate into tumor-associated macrophages (...

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Detalles Bibliográficos
Autores principales: Bess, Shelby N., Greening, Gage J., Rajaram, Narasimhan, Muldoon, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035255/
https://www.ncbi.nlm.nih.gov/pubmed/35461243
http://dx.doi.org/10.1186/s12865-022-00493-5