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Voclosporin: a novel calcineurin inhibitor with no impact on mycophenolic acid levels in patients with SLE

BACKGROUND: An open-label phase 1 study was conducted to evaluate the effect of voclosporin following dosing with mycophenolate mofetil (MMF) on blood levels of mycophenolic acid (MPA, the active moiety of MMF) and MPA glucuronide (MPAG, the pharmacologically inactive metabolite of MMF) in subjects...

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Detalles Bibliográficos
Autores principales: van Gelder, Teun, Huizinga, Robert B, Lisk, Laura, Solomons, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035351/
https://www.ncbi.nlm.nih.gov/pubmed/33527141
http://dx.doi.org/10.1093/ndt/gfab022