Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system

The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas12a system is composed of a Cas12a effector that acts as a DNA-cleaving endonuclease and a crispr RNA (crRNA) that guides the effector to the target DNA. It is considered a key molecule for inducing target-specific gene editin...

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Detalles Bibliográficos
Autores principales: Kim, Hanseop, Lee, Wi-jae, Kim, Chan Hyoung, Oh, Yeounsun, Gwon, Lee Wha, Lee, Hyomin, Song, Woojeung, Hur, Junho K., Lim, Kyung-Seob, Jeong, Kang Jin, Nam, Ki-Hoan, Won, Young-Suk, Lee, Kyeong-Ryoon, Lee, Youngjeon, Kim, Young-Hyun, Huh, Jae-Won, Jun, Bong-Hyun, Lee, Dong-Seok, Lee, Seung Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035383/
https://www.ncbi.nlm.nih.gov/pubmed/35505967
http://dx.doi.org/10.1016/j.omtn.2022.03.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035383/
https://www.ncbi.nlm.nih.gov/pubmed/35505967
http://dx.doi.org/10.1016/j.omtn.2022.03.021

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