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Genomic Variations and Immune-Related Features of TMB, PD-L1 Expression and CD8(+) T Cell Infiltration in Chinese Pulmonary Sarcomatoid Carcinoma

BACKGROUND: Pulmonary sarcomatoid carcinoma (PSC) is a rare and distinct subtype of lung cancer characterized by its aggressiveness and dismal prognosis. However, genomic landscape and immune contexture have not been fully elucidated among PSC patients. METHODS: In the present study, whole-exome-seq...

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Detalles Bibliográficos
Autores principales: Zhang, Chenyue, Li, Zhenxiang, Zhang, Yanxiang, Zhao, Chenglong, Wang, Hui, Lin, Jiamao, Liu, Cuicui, Wang, Xiaohui, Wang, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035462/
https://www.ncbi.nlm.nih.gov/pubmed/35480996
http://dx.doi.org/10.2147/IJGM.S357659