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Static Stretch Increases the Pro-Inflammatory Response of Rat Type 2 Alveolar Epithelial Cells to Dynamic Stretch

Background: Mechanical ventilation (MV) inflicts stress on the lungs, initiating or increasing lung inflammation, so-called ventilator-induced lung injury (VILI). Besides overdistention, cyclic opening-and-closing of alveoli (atelectrauma) is recognized as a potential mechanism of VILI. The dynamic...

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Detalles Bibliográficos
Autores principales: Ferreira, Jorge M. C., Huhle, Robert, Müller, Sabine, Schnabel, Christian, Mehner, Mirko, Koch, Thea, Gama de Abreu, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035495/
https://www.ncbi.nlm.nih.gov/pubmed/35480037
http://dx.doi.org/10.3389/fphys.2022.838834