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Hyperexcitable superior colliculus and fatal brainstem spreading depolarization in a model of Sudden Unexpected Death in Epilepsy

Cardiorespiratory arrest and death in mouse models of sudden unexpected death in epilepsy occur when spreading depolarization is triggered by cortical seizures and then propagates to the brainstem. However, the critical brain regions and the specific changes required to allow spreading depolarizatio...

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Detalles Bibliográficos
Autores principales: Cain, Stuart M., Bernier, Louis-Philippe, Zhang, Yiming, Yung, Andrew C., Kass, Jennifer, Bohnet, Barry, Yang, Yi, Gopaul, Rayshad, Kozlowski, Piotr, MacVicar, Brian A., Snutch, Terrance P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035526/
https://www.ncbi.nlm.nih.gov/pubmed/35474853
http://dx.doi.org/10.1093/braincomms/fcac006