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miR-29b-3p Inhibitor Alleviates Hypomethylation-Related Aberrations Through a Feedback Loop Between miR-29b-3p and DNA Methylation in Cardiomyocytes

As a member of the miR-29 family, miR-29b regulates global DNA methylation through target DNA methyltransferases (DNMTs) and acts as both a target and a key effector in DNA methylation. In this study, we found that miR-29b-3p expression was inversely correlated with DNMT expression in the heart tiss...

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Detalles Bibliográficos
Autores principales: Wu, Fang, Yang, Qian, Mi, Yaping, Wang, Feng, Cai, Ke, Zhang, Yawen, Wang, Youhua, Wang, Xu, Gui, Yonghao, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035530/
https://www.ncbi.nlm.nih.gov/pubmed/35478963
http://dx.doi.org/10.3389/fcell.2022.788799