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Circulating Autoantibodies Recognizing Immunodominant Epitopes From Human Apolipoprotein B Associate With Cardiometabolic Risk Factors, but Not With Atherosclerotic Disease

RATIONALE: Atherosclerosis is a chronic inflammatory disease of large arteries that involves an autoimmune response with autoreactive T cells and auto-antibodies recognizing Apolipoprotein B (ApoB), the core protein of low-density lipoprotein (LDL). Here, we aimed to establish a clinical association...

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Detalles Bibliográficos
Autores principales: Marchini, Timoteo, Malchow, Sara, Caceres, Lourdes, El Rabih, Abed Al Hadi, Hansen, Sophie, Mwinyella, Timothy, Spiga, Lisa, Piepenburg, Sven, Horstmann, Hauke, Olawale, Tijani, Li, Xiaowei, Mitre, Lucia Sol, Gissler, Mark Colin, Bugger, Heiko, Zirlik, Andreas, Heidt, Timo, Hilgendorf, Ingo, Stachon, Peter, von zur Muehlen, Constantin, Bode, Christoph, Wolf, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035541/
https://www.ncbi.nlm.nih.gov/pubmed/35479271
http://dx.doi.org/10.3389/fcvm.2022.826729