Cargando…

Circulating Autoantibodies Recognizing Immunodominant Epitopes From Human Apolipoprotein B Associate With Cardiometabolic Risk Factors, but Not With Atherosclerotic Disease

RATIONALE: Atherosclerosis is a chronic inflammatory disease of large arteries that involves an autoimmune response with autoreactive T cells and auto-antibodies recognizing Apolipoprotein B (ApoB), the core protein of low-density lipoprotein (LDL). Here, we aimed to establish a clinical association...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marchini, Timoteo, Malchow, Sara, Caceres, Lourdes, El Rabih, Abed Al Hadi, Hansen, Sophie, Mwinyella, Timothy, Spiga, Lisa, Piepenburg, Sven, Horstmann, Hauke, Olawale, Tijani, Li, Xiaowei, Mitre, Lucia Sol, Gissler, Mark Colin, Bugger, Heiko, Zirlik, Andreas, Heidt, Timo, Hilgendorf, Ingo, Stachon, Peter, von zur Muehlen, Constantin, Bode, Christoph, Wolf, Dennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035541/ https://www.ncbi.nlm.nih.gov/pubmed/35479271 http://dx.doi.org/10.3389/fcvm.2022.826729

Ejemplares similares

The Role of Tumor Necrosis Factor Associated Factors (TRAFs) in Vascular Inflammation and Atherosclerosis
por: Gissler, Mark Colin, et al.
Publicado: (2022)

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe(–/–) mice
por: Leipner, Julia, et al.
Publicado: (2021)

Risk‐Adjusted Comparison of In‐Hospital Outcomes of Transcatheter and Surgical Aortic Valve Replacement
por: Stachon, Peter, et al.
Publicado: (2019)

Elevated platelet–leukocyte complexes are associated with, but dispensable for myocardial ischemia–reperfusion injury
por: Starz, Christopher, et al.
Publicado: (2022)

Use and Outcomes of Acute Treatment Strategies in Patients with Severe Aortic Valve Stenosis
por: Piepenburg, Sven M., et al.
Publicado: (2021)

Modulating Autoimmunity against LDL: Development of a Vaccine against Atherosclerosis
por: Marchini, Timoteo, et al.
Publicado: (2021)

Inflammatory Cell Recruitment in Cardiovascular Disease
por: Marchini, Timoteo, et al.
Publicado: (2021)

Coronary magnetic resonance imaging after routine implantation of bioresorbable vascular scaffolds allows non-invasive evaluation of vascular patency
por: von zur Mühlen, Constantin, et al.
Publicado: (2018)

Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice
por: Tarkhnishvili, Aleksandre, et al.
Publicado: (2022)

Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
por: Pennig, Jan, et al.
Publicado: (2019)

Real-time magnetic resonance imaging – guided coronary intervention in a porcine model
por: Heidt, Timo, et al.
Publicado: (2019)

Publisher Correction: Real-time magnetic resonance imaging – guided coronary intervention in a porcine model
por: Heidt, Timo, et al.
Publicado: (2019)

Impact of the COVID-19 pandemic on aortic valve replacement procedures in Germany
por: Heidenreich, Adrian, et al.
Publicado: (2023)

Acute exposure to air pollution particulate matter aggravates experimental myocardial infarction in mice by potentiating cytokine secretion from lung macrophages
por: Marchini, Timoteo, et al.
Publicado: (2016)

Tumor Necrosis Factor Receptor Associated Factor 6 Is Not Required for Atherogenesis in Mice and Does Not Associate with Atherosclerosis in Humans
por: Stachon, Peter, et al.
Publicado: (2010)

Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging
por: Heidt, Timo, et al.
Publicado: (2016)

Established and Emerging Mechanisms of Diabetic Cardiomyopathy
por: Gollmer, Johannes, et al.
Publicado: (2019)

Mitochondrial Mechanisms in Diabetic Cardiomyopathy
por: Gollmer, Johannes, et al.
Publicado: (2020)

Impact of COVID-19 on Cardiovascular Disease
por: Vosko, Ivan, et al.
Publicado: (2023)

Residual inflammatory risk in coronary heart disease: incidence of elevated high-sensitive CRP in a real-world cohort
por: Peikert, Alexander, et al.
Publicado: (2019)

P2Y(12) Inhibition in Murine Myocarditis Results in Reduced Platelet Infiltration and Preserved Ejection Fraction
por: Schmidt, Sarah Nasreen, et al.
Publicado: (2021)

P2X(4) deficiency reduces atherosclerosis and plaque inflammation in mice
por: Peikert, Alexander, et al.
Publicado: (2022)

Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1
por: Pepin, Mark E., et al.
Publicado: (2019)

In-hospital outcomes of self-expanding and balloon-expandable transcatheter heart valves in Germany
por: Stachon, Peter, et al.
Publicado: (2021)

Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis
por: Günther, F., et al.
Publicado: (2017)

Cardiogenic shock: incidence, survival and mechanical circulatory support usage 2007–2017-insights from a national registry
por: Lang, Corinna N., et al.
Publicado: (2020)

P2Y(12)-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction
por: Seung, Hana, et al.
Publicado: (2022)

Cellular Heterogeneity of the Heart
por: Anto Michel, Nathaly, et al.
Publicado: (2022)

Molecular magnetic resonance imaging of activated platelets allows noninvasive detection of early myocarditis in mice
por: Maier, Alexander, et al.
Publicado: (2020)

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense
por: Wolf, Dennis, et al.
Publicado: (2018)

Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile
por: Merz, J., et al.
Publicado: (2021)

Coronary artery bypass grafting versus stent implantation in patients with chronic coronary syndrome and left main disease: insights from a register throughout Germany
por: Stachon, Peter, et al.
Publicado: (2021)

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression
por: Lindau, Alexandra, et al.
Publicado: (2016)

Two-year survival of patients screened for transcatheter aortic valve replacement with potentially malignant incidental findings in initial body computed tomography
por: Stachon, Peter, et al.
Publicado: (2015)

COVID-19 pandemic affects STEMI numbers and in-hospital mortality: results of a nationwide analysis in Germany
por: Oettinger, Vera, et al.
Publicado: (2022)

A logistic regression analysis comparing minimalistic approach and intubation anaesthesia in patients undergoing transfemoral transcatheter aortic valve replacement
por: Maier, Alexander, et al.
Publicado: (2020)

SIRT3 in Cardiac Physiology and Disease
por: Koentges, Christoph, et al.
Publicado: (2016)

CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies
por: Wolf, Dennis, et al.
Publicado: (2012)

Correction: CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies
por: Wolf, Dennis, et al.
Publicado: (2012)

Treatment of pure aortic regurgitation using surgical or transcatheter aortic valve replacement between 2018 and 2020 in Germany
por: Oettinger, Vera, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_aioa1v4h97gfbdddt8lsh085js