Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down‐Regulation of Bile Acid Synthesis

Activation of extracellular signal–regulated kinase (ERK) 1/2 promotes hepatocyte proliferation in response to growth stimuli, but whether constitutive hepatocyte ERK1/2 signaling functions in liver physiology is unknown. To examine the role of ERK1/2 in hepatic homeostasis, the effects of a knockou...

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Detalles Bibliográficos
Autores principales: Cingolani, Francesca, Liu, Yunshan, Shen, Yang, Wen, Jing, Farris, Alton B., Czaja, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035584/
https://www.ncbi.nlm.nih.gov/pubmed/34936222
http://dx.doi.org/10.1002/hep4.1867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035584/
https://www.ncbi.nlm.nih.gov/pubmed/34936222
http://dx.doi.org/10.1002/hep4.1867

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