Cargando…
Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down‐Regulation of Bile Acid Synthesis
Activation of extracellular signal–regulated kinase (ERK) 1/2 promotes hepatocyte proliferation in response to growth stimuli, but whether constitutive hepatocyte ERK1/2 signaling functions in liver physiology is unknown. To examine the role of ERK1/2 in hepatic homeostasis, the effects of a knockou...
Autores principales: | Cingolani, Francesca, Liu, Yunshan, Shen, Yang, Wen, Jing, Farris, Alton B., Czaja, Mark J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035584/ https://www.ncbi.nlm.nih.gov/pubmed/34936222 http://dx.doi.org/10.1002/hep4.1867 |
Ejemplares similares
-
ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?
por: Buscà, Roser, et al.
Publicado: (2016) -
Mouse liver injury induces hepatic macrophage FGF23 production
por: Kumar, Pradeep, et al.
Publicado: (2022) -
ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1
por: Buscà, Roser, et al.
Publicado: (2015) -
Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling
por: Yang, Ke-Yan, et al.
Publicado: (2022) -
OR26-3 ERK1/2-RSK2 Maintains Estrogen Homeostasis in the Adult Mammary Gland
por: Sandusky, Zachary
Publicado: (2019)