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Exploring the possible molecular targeting mechanism of Saussurea involucrata in the treatment of COVID-19 based on bioinformatics and network pharmacology

OBJECTIVE: Based on bioinformatics and network pharmacology, the treatment of Saussurea involucrata (SAIN) on novel coronavirus (COVID-19) was evaluated by the GEO clinical sample gene difference analysis, compound-target molecular docking, and molecular dynamics simulation. role in the discovery of...

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Detalles Bibliográficos
Autores principales: Zhang, Dongdong, Wang, Zhaoye, Li, Jin, Zhu, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035664/
https://www.ncbi.nlm.nih.gov/pubmed/35751193
http://dx.doi.org/10.1016/j.compbiomed.2022.105549