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Gasdermin E is required for induction of pyroptosis and severe disease during enterovirus 71 infection

Pyroptosis is an inflammatory form of programmed cell death that is executed by the gasdermin (GSDM)-N domain of GSDM family proteins, which form pores in the plasma membrane. Although pyroptosis acts as a host defense against invasive pathogen infection, its role in the pathogenesis of enterovirus...

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Detalles Bibliográficos
Autores principales: Dong, Siwen, Shi, Yujin, Dong, Xiaojing, Xiao, Xia, Qi, Jianli, Ren, Lili, Xiang, Zichun, Zhou, Zhuo, Wang, Jianwei, Lei, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035723/
https://www.ncbi.nlm.nih.gov/pubmed/35339492
http://dx.doi.org/10.1016/j.jbc.2022.101850