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Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways

OBJECTIVE: Although it is well established that urocortin 2 (Ucn2), a peptide member of the corticotrophin releasing factor (CRF) family, and its specific corticotrophin-releasing factor 2 receptor (CRF2R) are highly expressed in skeletal muscle, the role of this peptide in the regulation of skeleta...

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Detalles Bibliográficos
Autores principales: Lautherbach, Natalia, Gonçalves, Dawit A.P., Silveira, Wilian A., Paula-Gomes, Sílvia, Valentim, Rafael Rossi, Zanon, Neusa M., Pereira, Marcelo G., Miyabara, Elen H., Navegantes, Luiz C.C., Kettelhut, Isis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035725/
https://www.ncbi.nlm.nih.gov/pubmed/35390501
http://dx.doi.org/10.1016/j.molmet.2022.101492