Transcriptional regulation and small compound targeting of ACE2 in lung epithelial cells

Angiotensin-converting enzyme 2 (ACE2) is the receptor of COVID-19 pathogen SARS-CoV-2, but the transcription factors (TFs) that regulate the expression of the gene encoding ACE2 (ACE2) have not been systematically dissected. In this study we evaluated TFs that control ACE2 expression, and screened...

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Detalles Bibliográficos
Autores principales: Liang, Li-jun, Wang, Di, Yu, Hong, Wang, Jun, Zhang, Hui, Sun, Bei-bei, Yang, Fu-ying, Wang, Zheng, Xie, Da-wei, Feng, Rui-e, Xu, Kai-feng, Wang, Gui-zhen, Zhou, Guang-biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035780/
https://www.ncbi.nlm.nih.gov/pubmed/35468992
http://dx.doi.org/10.1038/s41401-022-00906-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035780/
https://www.ncbi.nlm.nih.gov/pubmed/35468992
http://dx.doi.org/10.1038/s41401-022-00906-6

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