Age-Related Downregulation of CCN2 Is Regulated by Cell Size in a YAP/TAZ-Dependent Manner in Human Dermal Fibroblasts: Impact on Dermal Aging

CCN2, a member of the CCN family of matricellular proteins, is a key mediator and biomarker of tissue fibrosis. We previously reported that CCN2 is significantly reduced in aged human dermis, which contributes to dermal aging through the downregulation of collagen production, the major structural pr...

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Detalles Bibliográficos
Autores principales: Qin, Zhaoping, He, Tianyuan, Guo, Chunfang, Quan, Taihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035808/
https://www.ncbi.nlm.nih.gov/pubmed/35480397
http://dx.doi.org/10.1016/j.xjidi.2022.100111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035808/
https://www.ncbi.nlm.nih.gov/pubmed/35480397
http://dx.doi.org/10.1016/j.xjidi.2022.100111

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