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Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury

Acute kidney injury (AKI) is a complex clinical disorder associated with poor outcomes. Targeted regulation of the degree of inflammation has been a potential strategy for AKI management. Macrophages are the main effector cells of kidney inflammation. However, macrophage heterogeneity in ischemia re...

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Detalles Bibliográficos
Autores principales: Yao, Weijian, Chen, Ying, Li, Zehua, Ji, Jing, You, Abin, Jin, Shanzhao, Ma, Yuan, Zhao, Youlu, Wang, Jinwei, Qu, Lei, Wang, Hui, Xiang, Chengang, Wang, Suxia, Liu, Gang, Bai, Fan, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036000/
https://www.ncbi.nlm.nih.gov/pubmed/35112806
http://dx.doi.org/10.1002/advs.202103675