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Prevention of Tumor Growth and Dissemination by In Situ Vaccination with Mitochondria‐Targeted Atovaquone

Atovaquone, an FDA‐approved drug for malaria, is known to inhibit mitochondrial electron transport. A recently synthesized mitochondria‐targeted atovaquone increased mitochondrial accumulation and antitumor activity in vitro. Using an in situ vaccination approach, local injection of mitochondria‐tar...

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Detalles Bibliográficos
Autores principales: Huang, Mofei, Xiong, Donghai, Pan, Jing, Zhang, Qi, Wang, Yian, Myers, Charles R., Johnson, Bryon D., Hardy, Micael, Kalyanaraman, Balaraman, You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036031/
https://www.ncbi.nlm.nih.gov/pubmed/35243806
http://dx.doi.org/10.1002/advs.202101267