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Prevention of Tumor Growth and Dissemination by In Situ Vaccination with Mitochondria‐Targeted Atovaquone
Atovaquone, an FDA‐approved drug for malaria, is known to inhibit mitochondrial electron transport. A recently synthesized mitochondria‐targeted atovaquone increased mitochondrial accumulation and antitumor activity in vitro. Using an in situ vaccination approach, local injection of mitochondria‐tar...
Autores principales: | Huang, Mofei, Xiong, Donghai, Pan, Jing, Zhang, Qi, Wang, Yian, Myers, Charles R., Johnson, Bryon D., Hardy, Micael, Kalyanaraman, Balaraman, You, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036031/ https://www.ncbi.nlm.nih.gov/pubmed/35243806 http://dx.doi.org/10.1002/advs.202101267 |
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