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Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D

While matrix stiffness regulates cell behavior on 2D substrates, recent studies using synthetic hydrogels have suggested that in 3D environments, cell behavior is primarily impacted by matrix degradability, independent of stiffness. However, these studies did not consider the potential impact of oth...

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Detalles Bibliográficos
Autores principales: Long, Hongyan, Vos, Bart E., Betz, Timo, Baker, Brendon M., Trappmann, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036035/
https://www.ncbi.nlm.nih.gov/pubmed/35187856
http://dx.doi.org/10.1002/advs.202105325