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The nuclease activity of DNA2 promotes exonuclease 1–independent mismatch repair

The DNA mismatch repair (MMR) system is a major DNA repair system that corrects DNA replication errors. In eukaryotes, the MMR system functions via mechanisms both dependent on and independent of exonuclease 1 (EXO1), an enzyme that has multiple roles in DNA metabolism. Although the mechanism of EXO...

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Detalles Bibliográficos
Autores principales: Kadyrova, Lyudmila Y., Dahal, Basanta K., Gujar, Vaibhavi, Daley, James M., Sung, Patrick, Kadyrov, Farid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036127/
https://www.ncbi.nlm.nih.gov/pubmed/35300981
http://dx.doi.org/10.1016/j.jbc.2022.101831