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EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer

The involvement of membrane-bound solute carriers (SLCs) in neoplastic transdifferentiation processes is poorly defined. Here, we examined changes in the SLC landscape during epithelial-mesenchymal transition (EMT) of pancreatic cancer cells. We show that two SLCs from the organic anion/cation trans...

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Detalles Bibliográficos
Autores principales: Nayak, Debasis, Weadick, Brenna, Persaud, Avinash K., Raj, Radhika, Shakya, Reena, Li, Junan, Campbell, Moray J., Govindarajan, Rajgopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036131/
https://www.ncbi.nlm.nih.gov/pubmed/35479410
http://dx.doi.org/10.1016/j.isci.2022.104193