Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

BACKGROUND: Complex innovative design trials are becoming increasingly common and offer potential for improving patient outcomes in a faster time frame. FOCUS4 was the first molecularly stratified trial in metastatic colorectal cancer and it remains one of the first umbrella trial designs to be laun...

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Detalles Bibliográficos
Autores principales: Brown, Louise C, Graham, Janet, Fisher, David, Adams, Richard, Seligmann, Jenny, Seymour, Matthew, Kaplan, Richard, Yates, Emma, Parmar, Mahesh, Richman, Susan D, Quirke, Philip, Butler, Rachel, Shiu, Kaikeen, Middleton, Gary, Samuel, Leslie, Wilson, Richard H, Maughan, Timothy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Design
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036145/
https://www.ncbi.nlm.nih.gov/pubmed/35083924
http://dx.doi.org/10.1177/17407745211069879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036145/
https://www.ncbi.nlm.nih.gov/pubmed/35083924
http://dx.doi.org/10.1177/17407745211069879

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