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Inhibition of O-GlcNAcylation Decreases the Cytotoxic Function of Natural Killer Cells

Natural killer (NK) cells mediate killing of malignant and virus-infected cells, a property that is explored as a cell therapy approach in the clinic. Various cell intrinsic and extrinsic factors affect NK cell cytotoxic function, and an improved understanding of the mechanism regulating NK cell fun...

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Detalles Bibliográficos
Autores principales: Feinberg, Daniel, Ramakrishnan, Parameswaran, Wong, Derek P., Asthana, Abhishek, Parameswaran, Reshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036377/
https://www.ncbi.nlm.nih.gov/pubmed/35479087
http://dx.doi.org/10.3389/fimmu.2022.841299