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Neutrophil Extracellular Trap Density Increases With Increasing Histopathological Severity of Crohn’s Disease

BACKGROUND: Intestinal neutrophil recruitment is a characteristic feature of the earliest stages of inflammatory bowel disease (IBD). Neutrophil elastase (NE) and myeloperoxidase (MPO) mediate the formation of neutrophil extracellular traps (NETs); NETs produce the bactericidal oxidant hypochlorous...

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Detalles Bibliográficos
Autores principales: Schroder, Angie L, Chami, Belal, Liu, Yuyang, Doyle, Chloe M, El Kazzi, Mary, Ahlenstiel, Golo, Ahmad, Gulfam, Pathma-Nathan, Nimalan, Collins, Geoff, Toh, James, Harman, Andrew, Byrne, Scott, Ctercteko, Grahame, Witting, Paul K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036391/
https://www.ncbi.nlm.nih.gov/pubmed/34724042
http://dx.doi.org/10.1093/ibd/izab239